A place to find out the latest developments from the generator of the white heat of scientific research that is the Heddle Lab
June 2017 We are pleased to announce that we have been awarded a prestigious FNP TEAM grant for a new DNA-origami based project where we hope to design and build DNA nanobots for novel uses including helping to build artificial cells. The research, carried out in collaboration with the group of Ilia Platzman at the Max Planck Institute for Medical Research aims to design and build functional systems built from DNA, which it is hoped, may have eventual applications in medicine and biotechnology. Thanks FNP!
June 2017 We have recently published a paper reviewing this topic in the Computational and Structural Biotechnology Journal. Playfully entitled "Resurrecting the Dead (Molecules)" the work explains how ancient molecules preserved in the environment can be recovered and analysed and how computational techniques can now be used to predict the identity of ancient molecules which can then be produced and tested. Read the paper here.
May 2017 More new positions! This time for making DNA nanorobots. More details can be found here
May 2017 Yusuke Sakai has succeeded in being awarded a prestigious Polonez fellowship to design and build novel DNA robots with potnetiual therepeutic use. Congratulations Yusuke!
May 2017 We are now seeking a postdcotoral researcher in biochemistry/structural biology to work on our OPUS-funded DNA gyrase project. More details, icluding application documents, can be found here Contact the Heddle lab for more information
April 2017 Protein cages are cool, cryo-EM is cool. Now find out how cool they are together in a new review paper published by members of the Heddle lab in partnership with our collaborator Kenji Iwasaki (Osaka University). The work was published in Current Opinion in Structural Biology.
November 2016: We are proud to announce that the Heddle lab has been awarded OPUS funding from NCN to investigate our favourite naturally ocurring nanomachine - DNA gyrase, this time the unusual forms found in the apicoplast
August 2016: We did it! The Heddle Lab was awarded one of the largest and most prestigious grants in Poland to carry out research into engineering proteins with unusual structural features.
July 2016: Dmitry Ghilarov has joined the lab after winning a prestigious Polonez grant to carry out research on DNA gyrase and their interaction with pentapeptide repeat proteins. You can access Dmitry`s POLONEZ pages here